Migraine affects up to 28% of adolescents. We’re enrolling children and teens aged 6–17 in a clinical trial to help evaluate investigational options for pediatric migraine under expert care.
Frequently asked questions
What is this study about?
This clinical research study is designed to evaluate the safety and effectiveness of an investigational medication for children and adolescents who experience migraine attacks. The goal is to better understand how the medication works in participants aged 6 to 17 years and how their bodies respond to it.
What is migraine?
Migraine is a neurological condition that can cause moderate to severe head pain, nausea, light or sound sensitivity, and other symptoms. In children and teens, migraines may affect school, sleep, and everyday activities.
How is the investigational medication given?
The investigational medication is taken orally. Participants may receive either the investigational medication or a placebo during the study.
What will my child be asked to do?
Your child will attend scheduled visits at our research clinic. These visits include study-related evaluations and safety monitoring conducted by trained medical professionals.
Is compensation included?
All study-related care, medical assessments, and investigational product are provided at no cost. Compensation for time and travel may be available.
Who may qualify for the study?
Your child may be eligible to participate if they are between 6 and 17 years of age. Have had migraine symptoms for at least 6 months. Experience between 1 and 14 migraine attacks per month.
How do I find out if my child qualifies?
Our research team will perform a screening process to determine if the study is a good fit for your child based on their health history and current condition.
What the clinic will ask you
Encore Medical Research's own pre-screening questions. You answer them when you apply — they go to the clinic only.
- Can your child swallow tablets (or can learn to do so)?NoYesUnsure
- Does your child experience between 1 and 14 migraine attacks per month with moderate to severe pain, in the last two months?YesNoUnsure
- Does your child have any of the following medical conditions? (check all that apply)Gastrointestinal issues that affect medication absorptionNone of the aboveChronic migraine with more than 15 headache days/monthRegular use of migraine medication beyond recommended limits (as defined in the last 3 months)Kidney failure requiring dialysisSuicidal thoughts or behaviors in the last 6 monthsHistory of seizures, stroke, or other neurological disordersLiver disease (especially severe liver issues)
- Does your child weigh between 44 and 298 pounds (20 to 135 kg)?YesUnsureNo
- Has your child been hospitalized three or more times in the past 6 months, specifically for migraine treatment?NoUnsureYes
- Has your child ever used medication (prescription or over-the-counter) to treat a migraine?UnsureNoYes
- Has your child had migraines (with or without aura) for at least 6 months, and do they typically last 3–72 hours if untreated?YesUnsureNo
- Has your child used any CGRP-inhibiting injectable treatments (like Aimovig®, Emgality®, etc.) in the last 6 months?UnsureYesNo
- If you answered yes to the previous question, please enter the previous medications used over the counter or by prescription.
- Is your child between 6 and 17 years old?NoYesUnsure
- Is your child currently participating in another clinical trial or has participated in one in the last 30 days?NoUnsureYes
