Living with extreme mood swings or manic episodes? A bipolar I disorder clinical trial is now enrolling adults in Miami and Broward. No-cost study-related care and expert clinical support are provided as part of this research study. Compensation for time and travel may also be available. Find out…
This bipolar I mood stabilizer study is evaluating an investigational treatment aimed at stabilizing mood and improving daily functioning for people living with manic depression. If you have been searching for a bipolar disorder clinical trial near me, this study may be enrolling close to you. Qualified participants may receive no-cost study-related assessments and close monitoring from experienced clinicians as part of this research study, which involves an investigational treatment being evaluated. Compensation is available. Signing up for this bipolar disorder research study takes only a few minutes. Review the eligibility criteria and take the first step toward potentially better mood management today.
Frequently asked questions
1. Who is this study mainly for?
This study is for adults 18–75 years old who have bipolar I or bipolar II disorder, are currently in remission or near remission but still have some lingering symptoms, and have been on a stable bipolar medication plan for at least 4 weeks. People also need to have had at least 3 mood episodes in their life and have a BMI of 22 or higher.
I have bipolar disorder, but my mood is not fully stable. Could I still qualify?
Possibly. The study is looking for people whose mood is mostly stable but with some residual symptoms, not people in a full depressive or manic episode. At screening, you’ll complete mood rating scales with the study doctor to confirm you’re in remission or near remission and not currently in a major episode. Final eligibility is based on these scores and the doctor’s judgment.
What mental health conditions might prevent me from joining?
You would not be able to join if you have a history of schizophrenia or another psychotic disorder, borderline personality disorder, or an eating disorder, or if you’ve had three or more mood episodes in the last year, suggesting persistent cycling. People with a moderate or severe substance or alcohol use disorder in the previous 6 months or who are considered at significant risk for suicide also cannot take part.
Are there medical conditions that could make me ineligible?
Yes. Certain thyroid, adrenal, liver, kidney, heart, eye, blood sugar, or stomach/intestinal problems may mean it isn’t safe to take part. Examples include type 1 diabetes, poorly controlled type 2 diabetes, serious liver disease, recent heart attack or stroke, pancreatitis, significant kidney disease, certain cancers, or serious diabetic eye disease. The study team will review your medical history, physical exam, and lab tests to decide if the study is safe for you.
What about pregnancy, birth control, and my current medications?
People of any sex assigned at birth can join, but those who can become pregnant cannot be pregnant or breastfeeding and must use acceptable birth control during the study. Some medicines and treatments are not allowed, including certain diabetes drugs (like GLP-1 medicines), recent weight-loss medications, and some brain-stimulation treatments (like ECT, ketamine/esketamine, or other neuromodulation) for the most recent mood episode. Your current bipolar medications must be stable, and the study doctor will review all of your medicines to see if any need to be adjusted or are not allowed.
