Living with focal epilepsy? Join our clinical trial testing an investigational treatment aimed at reducing seizure frequency and improving daily life. Expert care, no-cost participation, and personalized support included.
Frequently asked questions
Who can join this study?
Adults between 18 and 75 years old who have had focal epilepsy for at least one year and are currently experiencing at least 4 seizures per month may be eligible.
What kind of epilepsy qualifies?
You must have focal onset seizures, including focal aware, focal impaired awareness, or focal to bilateral tonic-clonic seizures, and meet the definition of drug-resistant epilepsy.
What medications or treatments can I be on?
You must be on a stable dose of 1 to 3 anti-seizure medications (ASMs) for at least 1 month before screening. Devices like VNS, DBS, or RNS and therapies like epilepsy diets or medical marijuana are allowed if they’ve been stable.
Do I need any recent tests or records?
Yes. You’ll need recent EEG, MRI or CT scans, and a record of your seizure history. If not available, these can be done during screening.
Are there health or lifestyle requirements?
You must weigh at least 40 kg (about 88 lbs), have a BMI under 35, be able to swallow tablets whole, and follow study instructions, including using a digital seizure diary daily.
What about birth control and pregnancy?
Women of childbearing potential and fertile men must use two forms of birth control during the study and for a period afterward. A negative pregnancy test is required before starting the study drug.
What the clinic will ask you
Encore Medical Research's own pre-screening questions. You answer them when you apply — they go to the clinic only.
- Are you (or the person you care for) between 18 and 75 years old?UnsureNoYes
- Are you currently taking 1 to 3 anti-seizure medications, with no recent changes in dose (past 30 days)?UnsureYesNo
- Do you also use any other epilepsy treatments like a special diet, a nerve stimulator (VNS/DBS/RNS), or surgery?NoUnsureYes
- Do you have at least 4 visible seizures every month, on average?YesUnsureNo
- Do your seizures include any of the following?Seizures that spread and become full body (tonic-clonic)Aware seizures with visible symptomsSeizures with impaired awarenessNone of the above
- Have you been diagnosed with focal onset epilepsy for at least 1 year?YesUnsureNo
- Have you had any of these in the last 6 months?Cluster or repetitive seizuresLiver, kidney, or serious stomach problemsSerious heart problemsSuicidal thoughts or attemptsSeizures caused by alcohol or drugsNone of the aboveStatus epilepticus (seizures lasting over 5–10 minutes)
- Have you tried 2 or more anti-seizure medications (ASMs) that didn’t fully control your seizures?UnsureYesNo
- In the past 2 months, have you had 21 days in a row with no seizures?YesNoUnsure
